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. 2013 Jan 9;8(1):e53055. doi: 10.1371/journal.pone.0053055

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© 2013 Yuan et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

After controlling for the Beck depression inventory-II (BDI) effect, increased cortical thickness was observed in several regions in late adolescence with online gaming addiction compared to healthy controls, i.e. the left precentral cortex, precuneus, middle frontal cortex, and inferior temporal and middle temporal cortices. In addition, reduced cortical thickness in the left lateral orbitofrontal cortex (OFC), insula cortex and lingual gyrus, along with the right postcentral gyrus, entorhinal cortex, and inferior parietal cortex were detected in late adolescence with online gaming addiction.