Table 2.
Changes in metabolic variables after six weeks, as compared with basal levels in the group of study
| S-dAGEs | L-dAGEs | T/Z* | p | |
|---|---|---|---|---|
| Biochemical data | ||||
| Glucose (mg/dl) | 4.55 ± 35.6 | –18 ± 56.7 | –1.21 | 0.24 |
| Total-cholesterol (mg/dl) | –9.0 ± 44.9 | 5.7 ± 43.3 | 0.84 | 0.41 |
| Triglycerides (mg/dl) | –3.7 ± 80.2 | 5.4 ± 59.0 | 0.33 | 0.74 |
| HDL-cholesterol (mg/dl) | –4.2 ± 10.3 | –2.5 ± 7.4 | 0.48 | 0.64 |
| HbA1c (%) | –0.11 ± 1.9 | 0.19 ± 1.3 | 0.46 | 0.65 |
| Metabolic markers | ||||
| Fluorescent serum AGEs (arbitrary units) | 0.68 ± 2.1 | 0.29 ± 1.3 | –0.57 | 0.57 |
| Malondialdehyde (µmol/l) | 2.0 ± 2.61 | –0.83 ± 2.0 | –3.12 | <0.005 |
| PCR (mg/l) | –1.21 ± 5.5 | –1.69 ± 5.4 | 0.23 | 0.82 |
| TNF-α (pg/ml) | 12.5 ± 14.7 | –18.36 ± 17.1 | –4.92 | <0.00001 |
| Insulin (µU/ml) | –7.0 ± 17.0 | –4.81 ± 7.3 | –0.67 | 0.5 |
| HOMA-IR | –2.5 ± 6.1 | –2.29 ± 3.7 | 0.13 | 0.89 |
| Dietary variables | ||||
| Kilocal/day | –222 ± 415.1 | –110 ± 307 | 0.78 | 0.44 |
| Carbohydrates (g/day) | –32.0 ± 73.2 | –23.6 ± 61.9 | 0.3 | 0.76 |
| Fats (g/day) | –6.1 ± 16.2 | 0.13 ± 20.6 | 0.85 | 0.4 |
| Proteins (g/day) | –9.6 ± 14.6 | –3.63 ± 22.0 | 0.82 | 0.42 |
| dAGEs (as CML, KU/day) | 2304 ± 4169 | –4990 ± 3380 | –4.9 | <0.00005 |
*Mann-Whitney U test.