Table 3.

HIV clinical disease progression and rate of hospital admissions

	Early treatment group (n=149)	Deferred treatment group (n=150)
CDC category C events
Incidence per 1000 patient-years	7·6 (2·5–23·6)	4·9 (1·2–19·7)
Number of children	3	2 (1, 1)
Pneumocystis jirovecii pneumonia	1	0
Disseminated penicilliosis	1	0
Severe sepsis	1	0
Oesophageal candidiasis	0	1 (1, 0)
Extrapulmonary tuberculosis	0	1 (0, 1)
CDC category B events
Incidence per 1000 patient-years	88 (61–122)	110 (80–147)
Number of children	20	32
Number of events	35	45 (34, 11)
Bacterial pneumonia	16	9 (7, 2)
Lymphoid interstitial pneumonia	9	0
Thrombocytopenia	1	10 (10, 0)
Herpes zoster	2	13 (9, 4)
Herpes simplex	1	6 (4, 2)
Complicated chickenpox	1	1 (1, 0)
Pulmonary tuberculosis	1	1 (1, 0)
Oral candidiasis	2	3 (1, 2)
Diarrhoea	1	2 (1, 1)
Molluscum contagiosum	1	0
Hospital admissions
Incidence per 1000 patient-years	123 (91–163)	88 (62–122)
Number of admissions	49	36
HIV related*	14	11
Antiretroviral adverse drug reactions	7	2
Not HIV related	28	23

Data are incidence (95% CI), n, or n (events before antiretroviral therapy, events after antiretroviral therapy). CDC=US Centers for Disease Control and Prevention.

^*One child in the early treatment group had six admissions for pneumonia, and subsequently died.