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(A) Multiple regulatory loci underlying the HTR could affect the plastically regulated processes sterol- and auxin homeostasis, the clock, ROS and blue light perception. (B) A single master regulatory locus, the COP9 signalosome subunit 5A underlying the HTR could affect all processes through differential deneddylation of the corresponding CRL complexes. Red circles denote expression regulation of the gene by the HTR. P denotes phosphorylation of CSN5A by OXI1.
