Table 1.
Differences in regional brain activity between interoceptive and exteroceptive attention in controls
| Anatomic region | Cluster | Co-ordinates (mm) |
|||||
|---|---|---|---|---|---|---|---|
| BA | Side | Size | Peak Z | x | y | z | |
| Interoception > exteroception | |||||||
| Paralimbic cluster | 7098 | ||||||
| Retrosplenial cortex | 30 | B | 6.60 | 27 | −51 | 12 | |
| Mid-cingulate | 6/23/24 | B | 5.57 | 15 | −12 | 51 | |
| Parahippocampus | 27 | B | 5.51 | −30 | −42 | −6 | |
| Auditory cortex | 42 | B | 5.45 | 45 | −24 | 24 | |
| Extrastriate | 17 | B | 5.29 | −24 | −51 | 6 | |
| Pulvinar of thalamus | – | B | 5.15 | −9 | −24 | 21 | |
| Insula | 48 | B | 5.05 | −33 | −6 | 15 | |
| Posterior cingulate | 23 | B | 4.59 | −12 | −60 | 15 | |
| Cerebellar vermis | – | B | 302 | 4.54 | −9 | −48 | −45 |
| Exteroception > interoception | |||||||
| Cerebellum/V1/extrastriate | 18/19 | B | 2838 | 6.38 | 3 | −81 | −27 |
| Superior and inferior parietal | 7 | L | 572 | 4.88 | −42 | −54 | 48 |
| DLPFC, operculum, ant. insula and caudate | 44/47/48/25 | L | 566 | 4.86 | −48 | 15 | 21 |
| Superior and inferior parietal | 7 | R | 379 | 4.82 | 45 | −48 | 54 |
| DLPFC, operculum, ant. insula | 44–46 | R | 757 | 4.44 | 36 | 57 | 18 |
| DMPFC and SMA | 8/6 | – | 304 | 4.06 | 0 | 18 | 63 |
| Operculum/ant. insula | 47/48 | R | 176 | 3.69 | 39 | 24 | 0 |
Note: R, right; L, left; B, bilateral; in the case of bilateral activations, the peak listed is for the side with the greater peak activation; V1, primary visual cortex; DLPFC, dorsolateral prefrontal cortex; DMPFC, dorsomedial prefrontal cortex; SMA, supplementary motor area.