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. Author manuscript; available in PMC: 2014 Jan 15.
Published in final edited form as: Bioorg Med Chem Lett. 2012 Dec 1;23(2):417–421. doi: 10.1016/j.bmcl.2012.11.084

Figure 2.

Figure 2

The active site of the hydrolase domain of human sEH complexed with 1. The Fo-Fc electron density map is contoured at 3σ. Hydrogen bonds are indicated by dashes. The structure reveals that the 2,4,6-trimethylphenyl group is directed into the hydrophobic environment, whereas the cycloheptyl moiety is exposed toward the solvent. Coordinates of the complex deposited as 4HAI with the Protein Data Bank. The image was produced using PYMOL.