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. 2010 Dec 1;13(11):1627–1637. doi: 10.1089/ars.2010.3219

FIG. 3.

FIG. 3.

Nrf2-induced radioresistance correlates with lower endogenous levels of ROS in A549 and H460 cells. (A, B) The A549 and H460 stable cells constitutively expressing control Luc-shRNA or Nrf2shRNA were exposed to ionizing radiation and ROS levels were determined 24 h post irradiation. A549 and H460 cells were exposed to a radiation dose of 10 Gy and ROS levels were measured by c-H2DCFDA staining and flow cytometry. *p ≤ 0.01 relative to the cells untreated Luc-shRNA cells; **p < 0.01 relative to the 0 Gy exposed untreated cells.