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. 2012 Oct 25;1(5):e001727. doi: 10.1161/JAHA.112.001727

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© 2012 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley-Blackwell.

This is an Open Access article under the terms of the Creative Commons Attribution Noncommercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 1. — Expression of leptin and its receptor (ObR) in a carotid fibroatheroma complicated by angiogenesis and intraplaque hemorrhage. A, Movat's pentachrome: a fibroatheromatous plaque with a large necrotic core (NC), intraplaque hemorrhage (HEM) (arrow), and overlying thick fibrous cap (FC). B, CD68-positive macrophages (MAC) within and surrounding the necrotic core. C, α-Actin-positive SMCs in the fibrous cap and remnants of media (arrowheads). D and E, Leptin (LEP) and its receptor (ObR), respectively. SMCs indicates smooth muscle cells.