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. 2012 Oct 25;1(5):e003434. doi: 10.1161/JAHA.112.003434

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© 2012 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley-Blackwell.

This is an Open Access article under the terms of the Creative Commons Attribution Noncommercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 6. — Net cholesterol bound to biglycan (associated with native TRL) at B_max as assessed from the solid-phase binding assay. Native TRL were isolated after intragastric saline and glucose (4%) infusion (fasted state) or intragastric intralipid (20%) and glucose (4%) infusion (fed state) in the lean and MetS JCR:LA-cp rats. B_max values (maximal binding capacity) were calculated from a solid-phase binding assay, which was standardized to a range of apoB48 concentrations to allow for generation of K_D and B_max values. For B_max values, see Table 3. Net cholesterol bound was calculated as the product of the B_max value for the respective TRL fraction and its cholesterol concentration. Different letter subscripts (a through d) all indicate a significant difference of P<0.05 between the groups according to 1-way ANOVA (n=3). MetS indicates metabolic syndrome. Values with the same letter subscript are not statistically different.