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. 2012 Oct 25;1(5):e004093. doi: 10.1161/JAHA.112.004093

Figure 3.

Figure 3.

Role of NO and eNOS in H2S restoration of ischemic limb blood flow. A, Blood flow from wild‐type animals after sodium sulfide (0.5 mg/kg) therapy with and without cPTIO (1 mg/kg) to scavenge NO. B, Blood flow from eNOS‐knockout (eNOS KO) animals with sodium sulfide therapy (0.5 mg/kg). C, Blood flow results from sodium sulfide–treated eNOS−/− animals plus 5 mg/kg L‐NAME (NOS inhibitor). D, Blood flow results from sodium sulfide–treated eNOS‐knockout animals plus 1 mg/kg cPTIO (NO scavenger). n=12, #P<0.05 compared from before to after ligation, *P<0.05 compared to either H2S+cPTIO or PBS controls.