Table 3.
Weight stable | Weight loss | 95% confidence interval {cutoff for 50% power} for mean difference (WL − WS) at 6 months |
||||
---|---|---|---|---|---|---|
Men | Women | Men | Women | Men | Women | |
(n = 12) | (n = 13) | (n = 12) | (n = 14) | |||
Log leptin, ng/mL | ||||||
Baseline | 1.53 (0.08) | 1.87 (0.08) | 1.37 (0.09) | 1.81 (0.08) | ||
6 months | 1.37 (0.09) | 1.88 (0.06) | 1.30 (0.10) | 1.74 (0.05) | (−0.37, 0.20) | (−0.31, 0.02)∧ |
{±0.29} | {±0.17} | |||||
Leptin, ng/mL | ||||||
Baseline | 39.72 (7.33) | 86.53 (12.86) | 26.54 (3.64) | 77.16 (12.17) | ||
6 months | 34.86 (7.16) | 91.80 (12.71) | 19.10 (2.14) | 63.90 (12.69) | ||
| ||||||
Log soluble leptin receptor, ng/mL | ||||||
Baseline | 1.35 (0.02) | 1.47 (0.04) | 1.34 (0.02) | 1.43 (0.04) | ||
6 months | 1.31 (0.05) | 1.53 (0.03) | 1.40 (0.06) | 1.49 (0.03) | (−0.06, 0.25) | (−0.14, 0.05) |
{±0.16} | {±0.10} | |||||
Soluble leptin receptor, ng/mL | ||||||
Baseline | 22.70 (1.02) | 30.44 (3.41) | 22.10 (0.71) | 28.68 (2.27) | ||
6 months | 21.99 (1.86) | 35.04 (2.68) | 24.82 (1.36) | 31.01 (2.08) | ||
| ||||||
Log adiponectin, mg/mL | ||||||
Baseline | 3.99 (0.06) | 4.15 (0.06) | 4.05 (0.07) | 4.17 (0.05) | ||
6 months | 4.02 (0.04) | 4.12 (0.05) | 4.04 (0.04) | 4.25 (0.05) | (−0.10, 0.14) | (−0.03, 0.29) |
{±0.12} | {±0.16} | |||||
Adiponectin, mg/mL | ||||||
Baseline | 11.41 (1.66) | 15.08 (2.12) | 12.13 (1.61) | 16.60 (1.87) | ||
6 months | 11.52 (1.51) | 14.82 (1.67) | 13.13 (1.90) | 18.06 (1.70) | ||
| ||||||
Log-free leptin index | ||||||
Baseline | 2.18 (0.09) | 2.41 (0.10) | 2.02 (0.10) | 2.38 (0.10) | ||
6 months | 2.06 (0.12) | 2.37 (0.06) | 1.90 (0.13) | 2.24 (0.05) | (−0.53, 0.22) | (−0.29, 0.04) |
{±0.38} | {±0.17} | |||||
Free leptin index | ||||||
Baseline | 177.26 (33.67) | 349.62 (75.91) | 125.74 (18.89) | 294.41 (51.15) | ||
6 months | 276.27 (150.28) | 272.86 (36.60) | 76.45 (6.65) | 213.85 (42.74) | ||
| ||||||
Log leptin : adiponectin ratio | ||||||
Baseline | 0.54 (0.11) | 0.73 (0.10) | 0.32 (0.12) | 0.65 (0.10) | ||
6 months | 0.37 (0.09) | 0.78 (0.08) | 0.24 (0.10) | 0.48 (0.08) | (−0.44, 0.17) | (−0.54, −0.05)* |
{±0.31} | {±0.25} | |||||
Leptin : adiponectin ratio | ||||||
Baseline | 4.12 (0.74) | 7.53 (1.76) | 2.82 (0.51) | 5.42 (0.96) | ||
6 months | 3.38 (0.64) | 6.73 (0.91) | 1.78 (0.30) | 4.23 (1.05) | ||
| ||||||
Log leptin/kg body fat | ||||||
Baseline | −0.02 (0.07) | 0.25 (0.08) | −0.28 (0.08) | 0.18 (0.08) | ||
6 months | −0.16 (0.10) | 0.24 (0.04) | −0.30 (0.12) | 0.21 (0.04) | (−0.50, 0.21) | (−0.16, 0.09) |
{±0.36} | {±0.13} | |||||
Leptin/kg body fat | ||||||
Baseline | 0.97 (0.13) | 2.06 (0.30) | 0.69 (0.10) | 1.77 (0.28) | ||
6 months | 0.83 (0.14) | 2.12 (0.29) | 0.62 (0.07) | 1.57 (0.20) |
Free leptin index = (leptin : soluble leptin receptor) × 100.
*Indicates P < 0.050 for comparison between groups within gender. (Note that P < 0.050 corresponds to the associated difference confidence interval not overlapping 0.00.)
∧Indicates P ≥ 0.050 to <0.100 for comparison between groups within gender.
The power is 50% if the absolute value of the true mean difference equals the half width of the respective 95% confidence interval.