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. 2012 Oct 19;35(1):72–80. doi: 10.3109/08923973.2012.677046

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© 2013 Informa Healthcare USA, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the source is credited.

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Figure 3. — Blebbastatin, ascorbic acid, and STS disrupt migration-related morphological change in neutrophils. (A) Fresh and aged plasma induced neutrophil morphological changes (n = 100 cells). (B) Blebbistatin, ascorbic acid, and STS abrogated plasma-induced morphological changes in neutrophils (n = 7 blood samples from 7 different volunteers; in triplicate). DMSO was used as a vehicle control. (C) Aged plasma induced a greater number of morphological changes than fresh plasma (*p < 0.05, compared with NLR-42D) (n = 5 blood samples from 5 different volunteers; in triplicate) (D) Blebbistatin, ascorbic acid, and STS significantly abrogated plasma-induced neutrophil morphological change, (*p < 0.05, compared with NLR-42D).