Table 1.
Target proteins of Fu Zi, Xi Xin, and Gui Zhi searched in PubChem.
| Active compounds | Homosapiens proteins name | GI number |
|---|---|---|
| Higenamine | D(2) dopamine receptor | 118206 |
|
| ||
| Fuziline | Orexin receptor type 1 | 222080095 |
|
| ||
| Caspase 8 | 2493531 | |
| Vitamin D3 receptor isoform VDRA | 63054845 | |
| Microtubule-associated protein tau | 92096784 | |
| Safrole | Corticotropin-releasing hormone receptor 2 | 38349113 |
| Aldehyde dehydrogenase 1 family, member A1 | 30582681 | |
| Euchromatic histone-lysine N-methyltransferase 2 | 168985070 | |
| Corticotropin releasing factor-binding protein | 30219 | |
|
| ||
| Farnesoid X nuclear receptor | 325495553 | |
| Methyleugenol | Sentrin-specific protease 8 | 262118306 |
| AR protein | 124375976 | |
|
| ||
| Asaricin | Cytochrome P450 3A4 isoform 1 | 13435386 |
|
| ||
| Sentrin-specific protease 8 | 262118306 | |
| Cytochrome P450 1A2 | 73915100 | |
| Asarinin | Cytochrome P450 2D6 isoform 1 | 40805836 |
| Cytochrome P450 2C9 precursor | 13699818 | |
| Cytochrome P450 2C19 precursor | 4503219 | |
|
| ||
| Transient receptor potential cation channel subfamily A member 1 | 313104269 | |
| cGMP-specific 3′,5′-cyclic phosphodiesterase | 317373261 | |
| Lamin isoform A delta 10 | 27436948 | |
| Cinnamaldehyde | Prothrombin | 339641 |
| Glucocorticoid receptor | 311348376 | |
| Aldehyde dehydrogenase 1 family, member A1 | 30582681 | |
| Chain A, crystal structure of the human 2-oxoglutarate oxygenase Loc390245 | 221046486 | |
| Glucocerebrosidase | 496369 | |
|
| ||
| Thromboxane-A synthase | 254763392 | |
| Heat shock protein HSP 90-alpha isoform 2 | 154146191 | |
| Melanocortin receptor 4 | 119508433 | |
| Lysosomal alpha-glucosidase preproprotein | 119393891 | |
| Alkaline phosphatase, tissue-nonspecific isozyme isoform 1 precursor | 116734717 | |
| Tyrosine-protein kinase ABL1 isoform a | 62362414 | |
| Nuclear receptor coactivator 3 isoform a | 32307126 | |
| Nuclear receptor coactivator 1 isoform 1 | 22538455 | |
| MPI protein | 16878311 | |
| Glyceraldehyde-3-phosphate dehydrogenase isoform 1 | 7669492 | |
| Glutathione S-transferase omega-1 isoform 1 | 4758484 | |
| Tyrosinase | 401235 | |
| Arachidonate 5-lipoxygenase | 126407 | |
| Carbonic anhydrase 2 | 115456 | |
| Cytochrome P450 2A6 | 308153612 | |
| Carbonic anhydrase 3 | 134047703 | |
| Carbonic anhydrase 6 | 116241278 | |
| Carbonic anhydrase 9 | 83300925 | |
| Hydroxycarboxylic acid receptor 2 | 74762622 | |
| Carbonic anhydrase 5B, mitochondrial | 8928041 | |
| Carbonic anhydrase 14 | 8928036 | |
| 5-hydroxytryptamine receptor 7 | 8488960 | |
| Epidermal growth factor receptor | 2811086 | |
| Carbonic anhydrase 7 | 1168744 | |
| Cinnamic acid | Carbonic anhydrase 5A, mitochondrial | 461680 |
| Tyrosine-protein phosphatase non-receptor type 1 | 131467 | |
| Carbonic anhydrase 4 | 115465 | |
| Carbonic anhydrase 1 | 115449 | |
| Adenosine receptor A2b | 112938 | |
| Lethal(3)malignant brain tumor-like protein 1 isoform I | 117938328 | |
| 5-hydroxytryptamine receptor 5A | 13236497 | |
| potassium voltage-gated channel subfamily H member 2 isoform d | 325651834 | |
| DNA polymerase iota | 154350220 | |
| DNA polymerase kappa | 7705344 | |
| DNA polymerase eta | 5729982 | |
| DNA polymerase beta | 4505931 | |
| Estrogen receptor beta isoform 1 | 10835013 | |
| Nuclear receptor subfamily 0 group B member 1 | 5016090 | |
| Thyroid hormone receptor beta | 189491771 | |
| 15-hydroxyprostaglandin dehydrogenase [NAD+] isoform 1 | 31542939 | |
| FAD-linked sulfhydryl oxidase ALR | 54112432 | |
| Ras and Rab interactor 1 | 68989256 | |
| Integrin alpha-4 precursor | 67191027 | |
| Chain A, human Ape1 endonuclease with bound abasic DNA And Mn2+ Ion | 6980812 | |
| Mcl-1 | 7582271 | |
| Chain A, structure of human Recq-like helicase in complex with a DNA Substrate | 282403581 | |
| Chain A, Jmjd2a tandem tTudor domains in complex with a trimethylated histone H4-K20 peptide | 162330054 | |
| Euchromatic histone-lysine N-methyltransferase 2 | 168985070 | |
| Chain B, the structure of wild-type human Hadh2 bound to Nad+ At 1.2 A | 122921311 | |
| Chain A, the structure of wild-type human Hadh2 bound to Nad+ At 1.2 A | 122921310 | |
| Bromodomain adjacent to zinc finger domain 2B | 6683500 | |
| Carbonic anhydrase 12 | 5915866 | |