Table 1. Differentially transcribed genes expressed at a higher level in early and late-exponential phase cultures of S. uberis 0140J compared with the S. uberis Vru mutant.

Gene*	Protein annotation	Early exponential growth phase		Late-exponential growth phase
		Fold change†	P value‡	Fold change†	P value‡
hasA/Sub1697	Hyaluronan synthase	380.0/250.2	<0.001	17.9/13.8	<0.001
hasB1/Sub1696	UDP-glucose 6-dehydrogenase 1	366.0/357.9	<0.001	8.5/8.1	0.006/<0.001
lbp/Sub0145	Lactoferrin-binding protein	255.1/153.8	<0.001	41.2/27.8	<0.001/0.1262
pauA/Sub1785	PauA protein precursor (streptokinase precursor)	169.6/168.3	<0.001	32.1/23.6	<0.001
Sub0051	Hypothetical protein	15.0/13.3	<0.001	16.6/10.5	<0.001/0.034
Sub0052	Membrane protein	14.8/14.5	<0.001	13.4/8.5	<0.001
Sub0177	RNA polymerase sigma factor protein	–	–	12.3/7.8	<0.001
Sub0176	Exported protein	–	–	9.4/6.6	<0.001
Sub1480	Permease	9.2/8.7	<0.001	8.1/4.1	<0.001
Sub1174	ABC transporter protein	8.3/4.2	0.033/0.002	16.4/12.9	<0.001
Sub0543	Dihydroxyacetone kinase subunit DhaK	–	–	8.7/5.2	<0.001
Sub1173	Membrane protein	–	–	8.5/6.7	0.027/<0.001
Sub0155	Basic membrane protein	8.1/7.7	<0.001	–	–
sclB/Sub1095	Collagen-like surface-anchored protein	6.9/6.5	0.012/<0.001	–	–
pyrD/Sub1264	Dihydroorotate dehydrogenase 1A	6.0/5.3	<0.001	–	–
Sub0118	Competence protein	–	–	5.6/4.5	<0.001
pyrF/Sub1025	Orotidine 5′-phosphate decarboxylase	5.4/5.0	<0.001	–	–
Sub0544	Dihydroxyacetone kinase family protein	–	–	4.9/4.4	<0.001
Sub0137	Lipoprotein	–	–	4.1/4.0	<0.001

^*Gene and protein annotation according to the genomic sequence of S. uberis 0140J (Ward et al., 2009).

^†Mean fold change represented by S. uberis 0140J versus the S. uberis vru mutant for each of the probes tested.

^‡Where the P value for data from one of the two probes is not in excess of 0.001, the mean of both P values is provided.