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. Author manuscript; available in PMC: 2013 Dec 28.
Published in final edited form as: Open Immunol J. 2012 Dec 28;5:46–54. doi: 10.2174/1874226201205010046

Figure 1. The Aspergillus fumigatus sensitization and inhalation model.

Figure 1

Naïve BALB/c mice (N) received neither sensitization nor conidia challenge. Mice were sensitized with subcutaneous (SC) and intraperitoneal (IP) immunizations of soluble A. fumigatus antigen in alum followed by 5 intranasal (IN) inoculations with soluble antigen in saline. For inhalation (IH) challenge, each of the six treatment groups were exposed to airborne A. fumigatus for 10 min. B lymphocyte numbers along with Ab production were assessed at day 0 (before IH challenge) and at days 3, 5, 7, 9, 11, and 13 after conidia challenge.