Figure 5. Experimental design of survival analysis.
Expression phenotypes were measured in blood samples drawn at recruitment. G×AI analyses were based on cross-sectional data for this time point, using the range of ages at recruitment (15–94ya). Longitudinal disease incidence and mortality data were collected for the cohort over the subsequent ~16y follow-up period. Cox proportional hazards analysis was performed for hazards including the prospective effect of baseline expression levels of UBQLNL and genotype for associated SNPs.