. Author manuscript; available in PMC: 2013 Sep 1.

Published in final edited form as: Mech Ageing Dev. 2012 Jul 31;133(9-10):581–590. doi: 10.1016/j.mad.2012.07.005

Table 4.

Cox proportional hazards analysis

Hazard: UBQLNL expression level (N=1,232)a
		Odds ratios

Outcome	N, outcome	Sex=male	BMI^b	Diabetes	Smoking	UBQLNL
Mortality, all causes	104	1.812^*	1.014	1.234	1.316	1.304^*
Mortality, cancer	30	1.408	1.047	1.028	0.832	1.547^*
Mortality, CVD	62	2.086^*	1.053^*	1.848	1.603	1.062
Cancer, mortality and morbidity	73	0.759	1.032	0.974	1.166	1.450^§

Hazard: rs7939159 genotype (N=1,196)^a

		Odds ratios

Outcome	N, outcome	Sex=male	BMI^b	Diabetes	Smoking	SNP^c

Mortality, all causes	98	1.950^§	1.024	1.237	1.380	1.514^*
Mortality, cancer	32	1.278	1.048	1.263	1.110	1.894^*
Mortality, CVD	62	2.868^§	1.072^§	1.679	1.581	0.964
Cancer, mortality and morbidity	77	0.734	1.032	1.082	1.252	2.080^†

Some participants excluded due to missing data.

Average BMI across all clinic visits.

Other SNPs not significant hazards (data not shown).

P<0.05

^§

P<0.01

^†

P<0.0001 No superscript=not significant.