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. 2012 Nov;87(11):1106–1117. doi: 10.1016/j.mayocp.2012.07.016

TABLE 3.

Risk Factors for Recurrent Clostridium difficile Infection

Age >65 y
Previous episodes of C difficile infection
History of severe C difficile infection
Increasing peripheral leukocyte count
Hypoalbuminemia
Fever
Presence of comorbid conditions
Inflammatory bowel disease
Ongoing or recurrent antibiotic exposure
Decreased serum anti–toxin A IgG
Use of acid suppression medications (controversial)