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. 2012 Jul 31;62(1):125–135. doi: 10.1007/s00262-012-1319-0

Table 3.

Characterization of tumor for newly diagnosed glioblastoma patients

Patient ID Ag expression on tumor (peptide HLA restriction) Biomarker characterization
HLA type AIM2 (A1) gp100 (A1) MAGE (A2) TRP-2 (A2) HER2 (A2) ILRa2 (A2) MGMT PTEN
2 A2+ + + + + + + UnMet RETAINED
4 A1+ + + + + + + UnMet N/A
6 A2+ + + Wk + + + Met RETAINED
7 A2+ + + + + + + Met LOSS
9 A2+ + + + + Met RETAINED
10 A2+ + + Wk + + + INV RETAINED
11 A2+ + + + + + + UnMet LOSS
12 A2+ + + Wk + + + UnMet RETAINED
13 A1+ + Wk Wk + + + NT LOSS
14 A1+ + + + + + NT LOSS
15 A1+ + + + + + INV RETAINED
16 A1 + A2+ + + Wk + + + Met LOSS
17 A2+ + Wk + NT LOSS
18 A1+ + Wk Wk + + + NT LOSS
19 A2+ + + Wk + + + Met RETAINED
20 A2+ + + Wk + + + Met RETAINED

Positive (+), negative (−), weak (Wk)

UnMet unmethylated, Met methylated, INV invalid results, NT not tested