TABLE 1.
Characteristics of Patients from the SEER Database by LN Involvementa
| Characteristic | No. (%) of patientsb |
P value | ||
|---|---|---|---|---|
| Total (N=107,705) | LN negative (n=63,944) | LN positive (n=43,761) | ||
| Median follow-up (mo) (IQR) | 99 (72-140) | 106 (80-149) | 87 (63-122) | |
| Year of diagnosis | <.001 | |||
| 1990-1994 | 24,695 (22.9) | 15,415 (24.1) | 9280 (21.2) | |
| 1995-1999 | 34,497 (32.0) | 21,867 (34.2) | 12,630 (28.9) | |
| 2000-2003 | 48,513 (45.0) | 26,662 (41.7) | 21,851 (49.9) | |
| Patient age (y) | <.001 | |||
| ≤50 | 40,808 (37.9) | 21,516 (33.6) | 19,292 (44.1) | |
| >50 | 66,897 (62.1) | 42,428 (66.4) | 24,469 (55.9) | |
| Race | <.001 | |||
| White | 88,390 (82.1) | 53,253 (83.3) | 35,137 (80.3) | |
| Black | 9294 (8.6) | 4739 (7.4) | 4555 (10.4) | |
| Othersc | 9676 (9.0) | 5746 (9.0) | 3930 (9.0) | |
| Unknown | 345 (0.3) | 206 (0.3) | 139 (0.3) | |
| Tumor size (mm) | <.001 | |||
| 0-20 | 67,723 (62.9) | 47,967 (75.0) | 19,756 (45.1) | |
| 21-30 | 22,868 (21.2) | 10,617 (16.6) | 12,251 (28.0) | |
| 31-40 | 8402 (7.8) | 3042 (4.8) | 5360 (12.2) | |
| 41-50 | 3835 (3.6) | 1189 (1.9) | 2646 (6.0) | |
| 51-60 | 2,102 (2.0) | 511 (0.8) | 1591 (3.6) | |
| 61-80 | 1798 (1.7) | 405 (0.6) | 1393 (3.2) | |
| >80 | 977 (0.9) | 213 (0.3) | 764 (1.7) | |
| Grade | <.001 | |||
| I | 14,029 (13.0) | 10,652 (16.7) | 3377 (7.7) | |
| II | 40,692 (37.8) | 25,113 (39.3) | 15,579 (35.6) | |
| III and UD | 45,391 (42.1) | 23,110 (36.1) | 22,281 (50.9) | |
| Unknown | 7593 (7.0) | 5069 (7.9) | 2524 (5.8) | |
| ER status | <.001 | |||
| Negative | 29,679 (27.6) | 16,973 (26.5) | 12,706 (29.0) | |
| Positive | 78,026 (72.4) | 46,971 (73.5) | 31,055 (71.0) | |
| PR status | <.001 | |||
| Negative | 38,748 (36.0) | 22,276 (34.8) | 16,472 (37.6) | |
| Positive | 68,957(64.0) | 41,668 (65.2) | 27,289 (62.4) | |
| No. of LNs dissected | <.001 | |||
| 4-10 | 32,292 (30.0) | 21,503 (33.6) | 10,789 (24.7) | |
| 11-20 | 57,534 (53.4) | 33,324 (52.1) | 24,210 (55.3) | |
| ≥21 | 17,879 (16.6) | 9117 (14.3) | 8762 (20.0) | |
a
ER = estrogen receptor; IQR = interquartile range; LN = lymph node; PR = progesterone receptor; SEER = Surveillance, Epidemiology and End Results; UD = undifferentiated.
b
Data are presented as No. (percentage) of patients unless otherwise indicated.
c
Including American Indian, Alaska Native, Asian, and Pacific Islander.