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. Author manuscript; available in PMC: 2013 Dec 15.
Published in final edited form as: Int J Cancer. 2012 Jun 28;131(12):2774–2784. doi: 10.1002/ijc.27580

Table 1. Demographic characteristics of patients and tumors.

Liver function was categorized by Child-Pugh classification and the tumors were also staged by means of the pTNM system. At least every 3 months, diagnostic imaging and blood sampling was done to check for HCC recurrence. Asterisks indicate significant differences (*1, p=0.0033, *2, p=0.042, *3, p=0.008).

Total HCC patients Suppressed
pSTAT1 group
control group
Total number 29 7 22
Male/Female 21 / 8 6 / 1 15 / 7
Age (year) 61.6 ± 10.3 66.5 ± 8.0 60.2 ± 10.8
Etiology (HBV/HCV) 11 / 15 3 / 5 8 / 10
Non-tumor lesion
(normal/CH/LC)
2 /18 /9 0 / 6 / 1 2 /12 / 8
ALT 44.0 ± 30.0 41.1 ± 21.0 46.2 ± 33.2
Platelets 15.7 ± 5.8 14.7 ± 1.9 16.0 ± 5.6
Child (A/B/C) 20 / 3 / 6 7 / 0 / 0 13 / 3 / 6
Stage (l / ll / lll / IV) 2 / 16 / 10 / 1 0 / 6 / 1 / 0 2 / 10 / 9 / 1
HCC recurrence
(within/over 2 years)
15 / 14 7 / 0 *1 8 / 14
Tumor size (cm) 4.8 ± 2.6 5.5 ± 2.4 4.6 ± 2.3
Macroscopic classification
(simple/surr/multi/invasive)
6 / 13 / 6 / 4 1 / 5 / 0 / 1 5 / 8 / 6 / 3
Capsule formation (+/−) 20 / 9 7 / 0 *2 13 / 9
Histology(moderate/poor) 10 / 19 3 / 4 7 / 15
AFP 1337 ± 4402 766 ± 579 1637 ± 5161
Vessel invasion (Vv +/−) 1 /28 0 / 7 1 / 21
Vessel invasion (Vp +/−) 9 / 20 5 / 2 *3 4 / 18