Table 2.
Gastric inflammation scores in mice after immunization and infection
| Group |
Inflammation score fundus1 |
Inflammation score antrum1 |
Overall mean inflammation score/group | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | ||
|
rUreB |
1 |
6 |
2 |
0 |
7 |
2 |
0 |
0 |
0.66 |
|
rNapA |
4 |
6 |
0 |
0 |
8 |
2 |
0 |
0 |
0.40 |
|
Lysate |
1 |
4 |
3 |
0 |
2 |
5 |
1 |
0 |
1.06 |
|
Sham-immunized |
1 |
5 |
4 |
0 |
5 |
5 |
0 |
0 |
0.90 |
| Negative control | 10 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 0.00 |
1Shown are the number of animals per group with a specific overall inflammation score in antrum and/or fundus: animals vaccinated with rUreB (n = 9), rNapA (n = 10) or lysate (n = 8), sham-immunized and infected controls (n = 10) and negative controls (n = 10). 0, no infiltration of mononuclear and/or polymorphonuclear cells; 1, mild diffuse infiltration of mononuclear and/or polymorphonuclear cells; 2, moderate diffuse infiltration of mononuclear and/or polymorphonuclear cells and/or the presence of one or two inflammatory aggregates; 3, marked diffuse infiltration of mononuclear and/or polymorphonuclear cells and/or the presence of at least three inflammatory aggregates.