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. 2012 Nov 28;11:91. doi: 10.1186/1475-925X-11-91

Figure 10.

Figure 10

Assessment of the algorithm sensitivity (specificity (SPC), sensitivity (TPR)) to changes in: a) ROI position in the axes of rows and columns (Δm, Δn) in the range of ±20 pixels and b) ROI size in the axes of rows and columns (ΔM, ΔN) in the range of ±20 pixels. The presented graph a) suggests many conclusions concerning the impact of the change in the position of the ROI on sensitivity and specificity. For example, the ROI shift in the range of ±10 pixels in the row or column axis slightly affects the values of specificity and sensitivity (changes at below 0.05). The figure b) shows that an increase in the size of the ROI by 13 pixels in rows or by 7, 8 pixels in rows and columns causes a significant increase in specificity and sensitivity by approximately 0.03. The analysis of this graph a) and the graph b) indicates that the areas were properly marked by an expert. In another case, the maximum values of sensitivity and specificity for the shift 0 and the change of size 0 of the marked ROI were not visible.