Table 2. Enrichment of kinase recognition motifs with specific preferences for disorder and phosphorylation variation.
Variation | Disorder | Benj. Hoch. FDR | Names |
−0.16 | 0.06 | 3.20E-03 | Akt kinase |
−0.27 | −0.33 | 7.67E-05 | ALK kinase |
−0.15 | 0.00 | 6.19E-05 | b-Adrenergic Receptor kinase |
−0.13 | 0.03 | 7.49E-05 | Calmodulin-dependent protein kinase II |
−0.22 | 0.01 | 2.71E-10 | Casein kinase II |
−0.04 | 0.05 | 1.88E-05 | Casein Kinase II |
0.52 | 0.10 | 6.32E-03 | CDK5 kinase |
0.07 | 0.05 | 2.88E-03 | DNA dependent Protein kinase |
−0.24 | −0.52 | 5.72E-05 | EGFR kinase |
0.07 | 0.07 | 6.97E-07 | ERK1,2 Kinase |
0.04 | 0.05 | 2.15E-05 | G protein-coupled receptor kinase 1 |
0.01 | 0.08 | 5.73E-04 | Growth associated histone HI kinase |
0.03 | 0.06 | 1.76E-03 | GSK3 kinase |
0.11 | 0.07 | 1.04E-09 | GSK-3, ERK1, ERK2, CDK5 |
−0.12 | −0.35 | 1.76E-03 | JAK2 kinase |
−0.18 | 0.05 | 1.84E-03 | MAPKAPK1 kinase |
0.03 | 0.05 | 4.63E-03 | MAPKAPK2 kinase |
−0.10 | 0.03 | 1.26E-05 | PKA kinase |
−0.09 | 0.02 | 8.09E-05 | PKC kinase |
−0.08 | −0.18 | 1.83E-04 | Src kinase |
The enrichment of kinase substrate motifs with specific preferences for disorder and phosphorylation variation was calculated with the 2D annotation enrichment technique. The multiple hypotheses-corrected p-values are reported.