Table 2.
Multivariate analysis prognostic factors in overall and disease-free survival of patients treated for gastric cancer
|
Variable |
Overall survival |
Disease-free survival |
||
|---|---|---|---|---|
| HR (CI 95%) | P | HR (CI 95%) | P | |
|
Perineural invasion | ||||
| No |
1.0 |
|
1.0 |
|
| Yes |
2.03 (1.17-3.53) |
0.011 |
2.46 (1.46-4.15) |
0.00 |
|
Extended resection | ||||
| No |
1.0 |
|
1.0 |
|
| Yes |
2.40 (1.31-4.38) |
0.004 |
2.58 (1.46-4,56) |
0.001 |
|
Treatment modality | ||||
| Surgery only |
1.61 (0.85-3.04) |
0.142 |
* |
* |
| Adjuvant CT/RT |
1.0 |
|
* |
* |
|
N-category – N-ratio | ||||
| N0-NR0 |
1.0 |
0.021 |
1.0 |
0.008 |
| N1-NR1a |
0.72 (0.16-3.17) |
0.661 |
0.65 (0.15-2.86) |
0.568 |
| N1-NR1b |
1.92 (0.73-5.05) |
0.184 |
2.01 (0.81-4.96) |
0.131 |
| N2-NR1 |
0.51 (0.14-1.81) |
0.297 |
0.41 (0.20-1.44) |
0.167 |
| N2-NR2 and NR3 |
2.02 (0.93-4.39) |
0.076 |
2.26 (1.10-4.63) |
0.026 |
| N3a – NR2 and NR3 |
2.78 (1.31-5.89) |
0.008 |
2.66 (1.30-5.44) |
0.007 |
| N3b – NR3 | 2.96 (1.08-8.12) | 0.036 | 2.77 (1.03-7.44) | 0.043 |