Table 1. Sensitivity of rK39 RDT and CLA ELISA in samples from infected and uninfected dogs.
| n (N) | CLA ELISA | rK39 RDT | |
| % (95% CI) | % (95% CI) | ||
| Infected dogs | 285 (54) | 85.3 (80.4–89.1) | 45.6 (36.8–54.7) |
| Uninfected endemic dogs | 29 (28) | - | 0 |
| Brazil non-endemic dogs | 8 (8) | - | 0 |
| UK non-endemic dogs | 30 (30) | - | 0 |
| Infected dogs by serological status1 | |||
| - seropositive | 243 (54) | - | 52.2 (42.1–62.0) |
| - seronegative | 42 (32) | - | 0 |
| Infected dogs by PCR status | |||
| - PCR positive | 111 (45) | 91.8 (85.0–95.6) | 58.6 (47.8–68.7) |
| - PCR negative | 74 (30) | 67.7 (53.5–79.3) | 26.3 (14.7–42.6) |
| Infected dogs by clinical status | |||
| - Symptomatic | 99 (39) | 95.3 (83.9–98.8) | 76.5 (63.8–85.7) |
| - Polysymptomatic | 39 (25) | 97.4 (82.6–99.7) | 88.9 (70.2–96.5) |
| - Oligosymptomatic | 60 (30) | 93.4 (79.7–98.1) | 69.1 (52.5–81.9) |
| - Asymptomatic | 178 (51) | 81.3 (75.0–86.4) | 32.6 (23.9–42.7) |
| Infected dogs by xenodiagnosis | |||
| - Infectious | 35 (18) | 100 | 77.7 (59.0–89.4) |
| - Non-infectious | 81 (27) | 80.6 (69.0–88.5) | 46.6 (32.0–61.8) |
The percentage of dogs positive (95% CI) by each test for different classes of dogs was estimated using general estimating equations with robust standard errors, to account for the non-independence of repeat samples from the same dog. n – number of samples; N – number of dogs.
1
as defined by CLA ELISA.