Figure 2. Details of the association results on chromosome 13 (A) and the X chromosome GRIA3 gene region (B) in the GAIN irritable vs. elated mania case-only analysis, as generated by SNAP 2.0.

The results for the chromosome 4 GABRG1 gene region in the GAIN irritable mania vs. control analysis are shown in (C). Physical position and gene annotations according to HapMap release 22 are shown along the x-axis, and −log (P value) is shown on the left y-axis. The most significant SNP is indicated as a large red diamond, and all other SNPs are colored according to linkage disequilibrium levels (r²) with the primary SNP, as calculated from HapMap Release 22 CEU population data, with darker red representing higher values. Recombination rate within the CEU samples is shown on the right y-axis in blue. RefSeq genes are shown with all possible exons and arrows indicating transcript direction.