Table 1.
Toxic agent |
Main + co-agents |
Main agents |
|
||
---|---|---|---|---|---|
n (%) | Total n (%) | Males n (%) | Females n (%) | p-value | |
Ethanol |
445 (42) |
194 (18) |
120 (22) |
74 (14) |
<0.001* |
BZD |
293 (28) |
160 (15) |
73 (14) |
87 (16) |
ns |
Paracetamol2 |
184 (17) |
116 (11) |
31 (6) |
85 (16) |
<0.001* |
Opioids |
152 (14) |
114 (11) |
80 (15) |
34 (6) |
<0.001* |
GHB |
96 (9) |
85 (8) |
67 (13) |
18 (3) |
<0.001* |
Neuroleptics |
99 (9) |
60 (6) |
15 (3) |
45 (9) |
<0.001* |
Anti-depressants |
106 (10) |
59 (6) |
16 (3) |
43 (8) |
<0.001* |
BZD derivates |
128 (12) |
58 (5) |
24 (4) |
34 (6) |
ns |
CO and fire smoke |
50 (5) |
48 (5) |
31 (6) |
17 (3) |
ns |
Amphetamine |
66 (6) |
25 (2) |
21 (4) |
4 (1) |
<0.001* |
Cardiovascular |
27 (3) |
18 (2) |
8 (1) |
10 (2) |
ns |
Anti-epileptics |
48 (5) |
17 (2) |
5 (1) |
12 (2) |
ns |
Cocaine |
30 (3) |
13 (1) |
10 (2) |
3 (1) |
ns |
NSAIDs |
54 (5) |
10 (1) |
3 (1) |
7 (1) |
ns |
Other gases |
13 (1) |
11 (1) |
4 (1) |
7 (1) |
ns |
Carisoprodol1 |
14 (1) |
8 (1) |
3 (1) |
5 (1) |
ns |
Scopolamine |
9 (1) |
8 (1) |
4 (1) |
4 (1) |
ns |
Anti-coagulants |
8 (1) |
7 (1) |
3 (1) |
4 (1) |
ns |
Lithium |
5 (<0.5) |
5 (<0.5) |
1 (<0.5) |
4 (1) |
ns |
Antihistamines |
54 (5) |
4 (<0.5) |
0 (0) |
4 (1) |
ns |
Insulin |
4 (<0.5) |
4 (<0.5) |
2 (<0.5) |
2 (<0.5) |
ns |
Other |
139 (13) |
41 (4) |
15 (3) |
26 (5) |
ns |
Total | 1065 (100) | 536 (100) | 529 (100) |
*Significant.
1Carisoprodol was taken off the market May 1st 2007.
2A codeine–paracetamol combination drug was the main agent in 29 cases.
Main agents present in ≤3 admissions were defined as “other”. In six cases, the main agent was unknown.
BZD vbenzodiazepines, GHB gamma-hydroxybutyric acid, NSAIDs non-steroidal anti-inflammatory drugs.
Of the opioids that were main agent, 79 were illegal substances. Of the legal opioids, 14 were methadone and none were buprenorphine. Of the anti-depressants as the main agent, 34 were selective serotonin reuptake inhibitors and 13 were tricycle anti-depressants.