Table 1. Methylation status of the genes studied and survival for the 30 patients studied.
Case | p16/INKa | BRCA1 | RARβ | MGMT | Hypermethylation in any gene | Survival (days) |
---|---|---|---|---|---|---|
1 |
|
X |
X |
|
X |
410 |
2 |
|
|
X |
X |
X |
322 |
3 |
|
X |
|
|
X |
200 |
4 |
|
|
|
|
|
55 |
5 |
|
X |
|
|
X |
174 |
6 |
X |
|
|
|
X |
412 |
7 |
|
X |
|
|
X |
374 |
8 |
|
|
X |
|
X |
777 |
9 |
|
|
|
|
|
386 |
10 |
|
|
X |
X |
X |
526 |
11 |
|
X |
|
|
X |
446 |
12 |
X |
|
|
|
X |
509 |
13 |
|
X |
X |
|
X |
36 |
14 |
X |
X |
|
X |
X |
230 |
15 |
|
X |
|
X |
X |
249 |
16 |
|
X |
|
X |
X |
89 |
17 |
X |
X |
|
X |
X |
59 |
18 |
|
X |
|
X |
X |
9 |
19 |
|
|
|
|
|
15 |
20 |
|
|
|
|
|
14 |
21 |
|
X |
X |
X |
X |
102 |
22 |
X |
|
X |
|
X |
85 |
23 |
|
X |
X |
X |
X |
302 |
24 |
|
|
|
X |
X |
1022 |
25 |
|
X |
X |
|
X |
419 |
26 |
|
X |
X |
|
X |
560 |
27 |
|
|
|
|
|
67 |
28 |
X |
|
X |
|
X |
3 |
29 |
|
|
X |
X |
X |
751 |
30 | X | X | X | 491 |
The boxes marked with a “X” indicate methylation, whereas white boxes correspond to unmethylation,