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. 2012 Dec 1;13(14):1471–1481. doi: 10.4161/cbt.22254

Table 1. Histological and immunohistochemical evaluation of HCT-116- and HT-29-driven colorectal tumors based on the data represented in Figures 5, 6, 7 and 8.

 
Tumor regression
p-ERK
p-MK2
Tunel
HCT-116
Vehicle
1
1–2
4
1
SB202190
2
2
3
2
Sorafenib
3
0–1
3
2
SB202190+Sorafenib 5 1 1 3
HT-29
Vehicle
1
1
4
2
SB202190
1–2
1–2
3
2
Sorafenib
2
0–1
2–3
3
SB202190+Sorafenib 3 0 2 4

Score: 5 = max; 0 = min.