Table 1. Histological and immunohistochemical evaluation of HCT-116- and HT-29-driven colorectal tumors based on the data represented in Figures 5, 6, 7 and 8.
|
Tumor regression |
p-ERK |
p-MK2 |
Tunel |
---|---|---|---|---|
HCT-116 | ||||
Vehicle |
1 |
1–2 |
4 |
1 |
SB202190 |
2 |
2 |
3 |
2 |
Sorafenib |
3 |
0–1 |
3 |
2 |
SB202190+Sorafenib | 5 | 1 | 1 | 3 |
HT-29 | ||||
---|---|---|---|---|
Vehicle |
1 |
1 |
4 |
2 |
SB202190 |
1–2 |
1–2 |
3 |
2 |
Sorafenib |
2 |
0–1 |
2–3 |
3 |
SB202190+Sorafenib | 3 | 0 | 2 | 4 |
Score: 5 = max; 0 = min.