Figure 4. (A) Effect of nelfinavir at 100 mg/kg (NFV+PBS) and supplementation with 10 mM of alanyl-glutamine (NFV+AQ) compared with control (PBS), on body weight variation during 7-d treatment. For each animal (n = 6), daily body weight was measured. (B) Effect of NFV and AQ supplementation (NFV+AQ) on jejunum villi area, villli height, crypt depth and (C) morphometry after 7 d of treatment. For each animal (n = 6), 10 measurements of each small intestine segment were taken. Values are expressed as percentage of control. *p < 0.05, compared with PBS control group, by student’s unpaired t-test. ^#p < 0.05, compared with group with NFV, by one-way ANOVA, with Bonferroni’s post test.