Table 3. Clinical and biological characteristics in 22 CLL patients with cell culture.
No. | Geneder | Age (years) | Binet stages | IGHV mutation status | Fludarabine-treated |
p53 mutation status | p53 deletion | ATM deletion | |
---|---|---|---|---|---|---|---|---|---|
p53 | p21 | ||||||||
1 |
Female |
78 |
A |
Mutated |
Yes |
Yes |
Wild type |
No |
No |
2 |
Female |
57 |
B |
Unmutated |
No |
No |
Mutated |
Yes |
Yes |
3 |
Female |
62 |
C |
Mutated |
Yes |
Yes |
Wild type |
No |
No |
4 |
Male |
83 |
B |
Mutated |
Yes |
No |
Mutated |
Yes |
No |
5 |
Female |
62 |
C |
Mutated |
Yes |
No |
Wild type |
No |
No |
6 |
Female |
52 |
C |
Unmutated |
Yes |
Yes |
Wild type |
No |
Yes |
7 |
Male |
48 |
C |
Unmutated |
No |
No |
Mutated |
Yes |
No |
8 |
Male |
58 |
C |
Unmutated |
No |
Yes |
Wild type |
No |
No |
9 |
Male |
50 |
A |
Mutated |
Yes |
Yes |
Wild type |
No |
No |
10 |
Female |
54 |
B |
Mutated |
Yes |
Yes |
Wild type |
No |
No |
11 |
Male |
80 |
C |
Unmutated |
Yes |
Yes |
Wild type |
No |
No |
12 |
Female |
70 |
B |
Unmutated |
No |
No |
Wild type |
No |
No |
13 |
Female |
67 |
A |
Mutated |
Yes |
Yes |
Wild type |
No |
No |
14 |
Female |
71 |
A |
Unmutated |
Yes |
Yes |
Wild type |
No |
No |
15 |
Male |
52 |
A |
Unmutated |
Yes |
Yes |
Wild type |
No |
No |
16 |
Male |
55 |
A |
Mutated |
Yes |
Yes |
Wild type |
No |
Yes |
17 |
Female |
61 |
C |
Mutated |
No |
No |
Wild type |
No |
No |
18 |
Male |
68 |
A |
Mutated |
Yes |
No |
Mutated |
No |
No |
19 |
Male |
53 |
C |
Mutated |
Yes |
Yes |
Wild type |
No |
No |
20 |
Male |
49 |
C |
Unmutated |
Yes |
No |
Mutated |
Yes |
No |
21 |
Female |
64 |
A |
Unmutated |
Yes |
Yes |
Wild type |
Yes |
No |
22 | Female | 57 | A | Mutated | Yes | Yes | Wild type | No | Yes |
“Yes” stands for raise up or positive; “No” stands for no change or negative.