Table 4.
Candidate genes involved in transmission phenotype segregated by polymorphisms and differential transcription
| Category | FL1 | St.M1 | Product | SNPs | candidate SNPs | SNP location | Homologs2 | BI3 |
|---|---|---|---|---|---|---|---|---|
|
Differentially transcribed genes |
AMF_433 |
AM579 |
Hypothetical protein |
1 |
0 |
Gene |
AP, ER, ECh |
TM |
| AMF_432 |
AM579 |
Hypothetical protein |
1 |
0 |
Gene |
AP, ER, ECh, ECa |
- |
|
| AMF_431 |
AM580 |
Hypothetical protein |
3 |
0 |
Gene |
AP, ER, ECh, ECa |
TM |
|
| AMF_430 |
AM576 |
Hypothetical protein |
22 |
0 |
Gene |
AP, ER, ECh, ECa |
TM/DS |
|
| AMF_429 |
AM574 |
Hypothetical protein |
15 |
0 |
Gene |
AP, ER, ECh |
TM |
|
| AMF_798 |
AM1055 |
Hypothetical protein |
9 |
0 |
Gene |
AP, ER, ECh, ECa |
TM/SP |
|
| AMF_879 |
AM1165 |
Hypothetical protein |
14 |
0 |
Gene |
- |
TM |
|
| AMF_878 |
AM1164 |
Outer membrane protein 4 |
2 |
0 |
Gene |
AP |
TM/SP |
|
| AMF_401 |
AM540 |
Hypothetical protein |
12 |
0 |
Gene/Prom |
- |
TM |
|
| AMF_258 |
AM347 |
Hypothetical protein |
19 |
0 |
Gene |
AP |
TM |
|
|
Differentially transcribed genes w/SNPs genescarrying candidate SNPs |
AMF_474 |
AM632 |
Ribosome-associated inhibitor A |
1 |
1 |
Promoter |
ER, ECh, ECa |
- |
| AMF_553 |
AM748 |
NADH Dehydrogenase I chain J |
1 |
1 |
Promoter |
AP, ER, ECh, ECa |
TM |
|
| AMF_793 |
AM1048 |
Hypothetical protein |
77 |
2 |
Gene/Prom |
AP, ER, ECh, ECa |
TM/SP |
|
| AMF_1026 |
AM1352 |
Hypothetical protein |
18 |
5 |
Gene/Prom |
AP, ER, ECh |
TM/DS |
|
| Genes carrying candidate SNPs | AMF_051 |
AM071 |
Hypothetical protein |
5 |
1 |
Gene |
AP, ER, ECh, ECa |
TM |
| AMF_197 |
AM265 |
Hypothetical protein |
19 |
1 |
Gene |
AP, RB |
TM |
|
| AMF_264 |
AM354 |
Hypothetical protein |
21 |
2 |
Gene |
ER, ECh, ECa |
TM/DS |
|
| AMF_265 |
AM356 |
Hypothetical protein |
65 |
1 |
Gene |
AP |
- |
|
| AMF_269 |
AM368 |
Hypothetical protein |
43 |
1 |
Gene |
RB |
TM/DS |
|
| AMF_480 |
AM644 |
DNA gyrase B |
14 |
1 |
Gene |
AP, ER, ECh, ECa, RB, RC, RR |
TM |
|
| AMF_530 |
AM712 |
Hypothetical protein |
138 |
1 |
Gene |
- |
TM |
|
| AMF_518 |
AM689 |
Hypothetical protein |
20 |
1 |
Gene |
AP |
- |
|
| AMF_547 |
AM742 |
Hypothetical protein |
1 |
1 |
Gene |
AP, ER, ECh, ECa |
DS |
|
| AMF_613 |
AM823 |
Hypothetical protein |
17 |
4 |
Gene |
AP, ER, ECh, ECa |
- |
|
| AMF_703 |
AM919 |
Hypothetical protein |
1 |
1 |
Gene |
AP, ER, ECh, ECa, RB, RC, RR |
TM |
|
| AMF_762 |
AM1001 |
methionyl-tRNA synthetase |
23 |
1 |
Gene |
AP, ER, ECh, ECa, RB, RC, RR |
TM/DS |
|
| AMF_764 |
AM1005 |
aspartokinase |
13 |
1 |
Gene |
AP, ER, ECh, ECa |
TM/DS |
|
| AMF_824 |
AM1091 |
D-Ala-D-Ala carboxypeptidase |
33 |
6 |
Gene |
AP, ER, ECh, ECa, RB, RC, RR |
TM/SP |
|
| AMF_893 |
AM1183 |
lipoprotein-releasing transmembrane protein |
8 |
3 |
Gene |
ER, ECh, ECa |
TM/DS |
|
| AMF_1037 | AM345 | Hypothetical protein | 4 | 1 | Gene | - | - |
1FL: Locus tag in the Florida strain St.M: locus tag in the St. Maries strain.
2AP: Anaplasma phagocytophilum, ER: Ehrlichia ruminantium, ECh: Ehrlichia chaffeensis, ECa: Ehrlichia canis, RB: Rickettsia bellii, RC: Rickettsia conorii, RR: Rickettsia rickettsia.
3BI: Bioinformatics TM: Transmembrane domain, SP: Signal peptide, Prom: promoter, DS: Deleterious substitution.