Table 1. Patient characteristics and clinical features.
| Variables | Test set (N, %) | P * | Validation set (N, %) | P * | Combined (N, %) | P * | |||
| Cases | Controls | Cases | Controls | Cases | Controls | ||||
| Age (years) | |||||||||
| ≤65 | 430 (57.3%) | 460 (55.2%) | 0.383 | 601 (64.2%) | 712 (67.2%) | 0.164 | 1031(61.2%) | 1172(61.9%) | 0.655 |
| >65 | 320 (42.7%) | 374 (44.8%) | 335 (35.8%) | 348 (32.8%) | 655 (38.8%) | 722 (38.1%) | |||
| Sex | |||||||||
| Male | 510 (68.0%) | 551 (66.1%) | 0.414 | 721 (77.0%) | 778 (73.4%) | 0.061 | 1231(73.0%) | 1329(70.2%) | 0.060 |
| Female | 240 (32.0%) | 283 (33.9%) | 215 (23.0%) | 282 (26.6%) | 455 (27.0%) | 565 (29.8%) | |||
| Site | |||||||||
| Cardia | 295 (39.3%) | 358 (38.3%) | 653 (38.7%) | ||||||
| Non-cardia | 455 (60.7%) | 578 (61.7%) | 1033(61.3%) | ||||||
| Histological types | |||||||||
| Diffuse | 406 (57.6%) | 539 (57.6%) | 945 (57.6%) | ||||||
| Intestinal | 299 (42.4%) | 397 (42.4%) | 696 (42.4%) | ||||||
| Depth of invasion | |||||||||
| T1 | 120 (17.4%) | 147 (15.7%) | 267 (16.4%) | ||||||
| T2 | 120 (17.4%) | 199 (21.3%) | 319 (19.6%) | ||||||
| T3 | 350 (50.7%) | 543 (58.0%) | 893 (55.0%) | ||||||
| T4 | 101 (14.5%) | 45 (5%) | 146 (9.0%) | ||||||
| Lymph node metastasis | |||||||||
| Positive | 333 (44.4%) | 371 (39.6%) | 704 (41.8%) | ||||||
| Negative | 417 (55.6%) | 565 (60.4%) | 982 (58.2%) | ||||||
| Distant metastasis | |||||||||
| M0 | 616 (87.3%) | 878 (93.8%) | 1494(91.0%) | ||||||
| M1 | 90 (12.7%) | 58 (6.2%) | 148 (9.0%) | ||||||
| TNM stage | |||||||||
| I | 189 (26.8%) | 259 (27.7%) | 448 (27.3%) | ||||||
| II | 155 (22.0%) | 185 (19.8%) | 340 (20.7%) | ||||||
| III | 250 (35.5%) | 395 (42.2%) | 645 (39.3%) | ||||||
| IV | 111 (15.7%) | 97 (10.3%) | 208 (12.7%) | ||||||
*
Two-sided χ2 test.