Table 2.
Logistic Regression Adjusted for Baseline Traditional Risk Factors Plus QRS at Year 0 and Incident QRS > 100 msec at Year 20
| Odds Ratio (95% CI) for Incident Prolonged QRS Duration at Year 20 | ||
|---|---|---|
| Year 0 Covariates | Model 1 (N=2501) |
Model 2 (N=1911) |
| Age (per 1 year) | 0.99 (0.95-1.03) | 1.01 (0.96-1.06) |
| White race (vs. Black) | 1.49 (1.10-2.02) | 1.63 (1.11-2.40) |
| Female sex (vs. Male) | 0.42 (0.28-0.63) | 0.71 (0.42-1.20) |
| SBP (per 1 mm Hg) | 1.00 (0.98-1.02) | 0.99 (0.97-1.01) |
| Diabetes | 0.60 (0.07-5.01) | 0.86 (0.09-7.94) |
| Creatinine (per 1 mg/dL) | 2.14 (0.90-5.09) | 2.04 (0.73-5.67) |
| BMI (per 1 kg/m2) | 0.97 (0.93-1.01) | 0.93 (0.88-0.98) |
| ECG LVMI (per 1 g/m2.7) | 1.10 (1.06-1.14) | 1.13 (1.08-1.18) |
| Current smoker (vs. not) | 1.29 (0.95-1.74) | 1.20 (0.84-1.73) |
| Antihypertensive therapy | 2.06 (0.95-4.49) | 1.90 (0.74-4.89) |
| QRS duration at Year 0 (per 10 msec) | 1.09 (1.07-1.11) | 1.10 (1.07-1.12) |
| Additional Covariates | ||
| CAC >0 at Year 20 | - | 0.94 (0.63-1.39) |
| Mean maximal CC-IMT at Year 20 | - | 1.52 (0.39-5.99) |
| Left Ventricular Diastolic Dimension (in mm) | - | 2.11 (1.43-3.11) |
| Left Ventricular Posterior Wall Thickness (in mm) | - | 3.72 (0.99-13.89) |
Abbreviations: SBP: systolic blood pressure; mm Hg: millimeters of mercury; mg/dL: milligrams per deciliter; BMI: body mass index; kg/m2: kilograms per meter squared; g/m: grams per meter; ECG LVMI: electrocardiographic left ventricular mass index; CAC: coronary artery calcium; CC-IMT: common carotid intima medial thickness