Table 2. Study outcomes: psoriasis and obesity.
| Study | Study period | Outcome ascertainment | Obesity in control patients (BMI in kg m−2) | Obesity in psoriasis patients (BMI in kg m−2) | Measure of association (95% CI) |
|---|---|---|---|---|---|
| aNaldi et al.17 | 1988–1997 | Interview/clinical examination | BMI⩾30: n=57 (8.3%) | BMI⩾30: n=71 (12.9%) | BMI⩾30: AOR 1.9 (1.2–2.8) |
| aHerron et al.14 | Not reported | Questionnaire | Mean BMI of 26.2 (s.d. 5.1) Median BMI of 25.7 | Mean BMI of 29.1 (s.d. 7.3) Median BMI of 27.8 | OR 2.39 (1.98–2.90) |
| aNeimann et al.18 | 1987–2002 | OXMIS/Read | BMI>30: Mild Ps: n=36 117 (13.1%) Severe Ps: n=1 093 (13.0%) | BMI>30: Mild Ps: n=13 404 (15.8%) Severe Ps: n=545 (20.7%) | BMI>30: Mild Ps: OR 1.29 (1.26–1.32) Mild Ps: AOR 1.27 (1.24–1.31) Severe Ps: OR 1.84 (1.60–2.11) Severe Ps: AOR 1.79 (1.55–2.05) |
| Cohen et al.11 | Not reported | Diagnosis in database | Obesity: n=1 561 (23.5%) | Obesity: n=100 (29.4%) | OR 1.4 (1.1–1.7) AOR 1.3 (1.0–1.7) |
| aKaye et al.15 | 1991–2005 | OXMIS/Read | BMI⩾30: n=11 996 (5.5%) | BMI⩾30: n=2 760 (6.3%) | BMI⩾30: HR 1.18 (1.14–1.23) |
| Cohen et al.12 | Not reported | Diagnosis of obesity in database | Obesity: n=1 768 (3.6%) | Obesity: n=1 419 (8.4%) | OR 2.4 (2.3–2.6) AOR 1.7 (1.5–1.9) |
| Xiao et al.23 | 1999–2007 | Medical code consistent with obesity | Obesity: n=183 (12.03) | Obesity: Mild Ps: n=227 (14.02%) Severe Ps: n=296 (20.10%) | Mild Ps: OR 1.41 (1.08–1.85) Mild Ps: AOR 1.42 (1.06–1.91) Severe Ps: OR 1.51 (1.15–1.98) Severe Ps: AOR 1.52 (1.13–2.04) |
| aDriessen et al.13 | Not reported | Manual chart review; BMI⩾30 | Mean BMI of 24.9 (s.d. not reported) | Mean BMI of 28.5 (s.d. not reported) | BMI⩾30: OR 5.49 (3.09–9.74) |
| Takahashi et al.21 | 2006–2008 | Manual chart review | Obesity: n=36 (22.7%) | Obesity: n=60 (39.7%) | OR 2.24 (1.36–3.69) |
| aSchmitt et al.19 | 2003–2004 | ICD-10 | Obesity: n=329 (10.5%) | Obesity: n=490 (15.6%) | OR 1.58 (1.36–1.83) AOR 1.63 (1.39–1.90) |
| aAugustin et al.10 | 2005 | ICD-10 | Obesity: n=136 118 (10.4%) | Obesity: n=6 055 (17.8%) | PR 1.72 (1.68–1.76) |
| aAl-Mutairi et al.9 | 2003–2007 | Manual chart review | BMI>30: n=195 (17%) | BMI>30: Mild Ps: n=372 (32.5%) Severe Ps: n=49 (41%) | BMI>30: Mild Ps: OR 2.36 (1.93–2.87) Severe Ps: OR 3.42 (2.30–5.10) |
| aWarnecke et al.22 | 2009–2010 | Questionnaire/clinical assessment | BMI>30: n=33 (33%) Mean BMI of 27.7 (s.d. 5.6) | BMI>30: n=44 (44%) Mean BMI of 30.1 (s.d. 7.7) | AOR 1.03 (0.97–1.09) |
| aZhang et al.24 | 1997–2009 | Clinical assessment | BMI⩾30: n=30 (2.6%); Mean BMI of 22.86 (s.d. 3.37) | BMI⩾30: n=179 (4.0%); Mean BMI of 23.29 (s.d. 3.25) | BMI⩾30: OR 1.68 (1.13–2.49) |
| aShapiro et al.20 | 1993–2006 | ICD-9 | Obesity: n=94 (8.7%) | Obesity: n=143 (13.3%) | OR 1.60 (1.22–2.11) AOR 1.32 (0.99–1.76) |
| Langan et al.16 | Not reported | Read codes (THIN database) | BMI 30–35: n=7 678 (20.5%) BMI>35: n=4 907 (13.1%) | BMI 30–35: n=887 (23.5%) BMI>35: n=662 (17.5%) | BMI>30: OR 1.38 (1.29–1.48) AOR 1.25 (1.16–1.34) |
Abbreviations: AOR, adjusted odds ratio; BMI, body mass index; CI, confidence interval; HR, hazard ratio; ICD, International Classification of Disease; OXMIS, Read, Oxford Medical Information System and Read diagnostic codes; PR: prevalence ratio; THIN, The Health Improvement Network database.
a
Denotes that obesity was the primary study outcome.