Table 1.
Examples Taken from the Previously Reported Intervals, Showing the Whole-Genome Association Statistics and Closest Gene to the Estimated Location of the Causal Agent Ŝ
| Chr | Reported LD Interval (Mb) | Interval Span (Mb) | WTCCC Ŝ | WTCCC p Value | NIDDK Ŝ | NIDDK p Value | Gene (WTCCC/NIDDK If different) |
|---|---|---|---|---|---|---|---|
| 1p31.3 | 67.36 – 67.77 | 0.41 | 67,684.8 | 2.1 × 10−11 | 67,707.3 | 3.0 × 10−10 | IL23Ra |
| 2q12.1 | 102.80 – 103.30 | 0.50 | 103,059.8 | 1.8 × 10−08 | 102,951.7 | 1.7 × 10−05 | IL18RAPa/IL1RL1a |
| 2q37.1 | 234.15 – 234.57 | 0.42 | 234,144.8 | 5.6 × 10−25 | 234,171.9 | 2.2 × 10−09 | ATG16L1a |
| 5q31.1 | 129.38 – 132.02 | 2.64 | 131,748.2 | 2.7 × 10−22 | 131,631.4 | 8.9 × 10−07 | C5orf56a/SLC22A4a |
| 16q12.1 | 50.46 – 50.85 | 0.39 | 50,803.2 | 2.6 × 10−15 | 50,803.2 | 1.1 × 10−09 | NOD2a |
| 50,846.3 | 1.6 × 10−13 | 50,846.5 | 4.1 × 10−04 | CYLD |
a
At least one of the estimated locations Ŝ is located within the identified gene. All locations in kb are in NCBI 37. Full details on the entire list of 71 LD intervals are given in Table S1.