Table I.

Dosage and duration of Lyme disease treatment

Clinical picture	Suggested regimens	Dosage	Administration	Durationof the treatment[days]
EM BLC	Doxycycline	100 mg bid	po	14-21
	Amoxicillin	500 mg tid (children: 50 mg/kg/day)	po	14-21
	Cefuroxime	500 mg bid (children: 30 mg/kg/day)	po	14-21
Lyme disease with joint involvement	Amoxicillin	500-1000 mg tid (children: 50 mg/kg/day)	po	14-28
	Doxycycline	100 mg bid or 200 mg q24h	po	14-28
	Cefuroxime	500 mg bid (children: 15 mg/kg/day)	po	14-28
Lyme disease with nervous system, heart or recurrent joint involvement	Ceftriaxone	2000 mg q24h (children: 50-75 mg/kg/day)	iv	14-28
	Cefotaxime	2000 mg tid (children: 150-200 mg/kg/day: divided in 3-4 doses)	iv	14-28
	Penicillin G	3-4 mu q4h (children: 0.2-0.4 mu/kg/day divided in 4- 6 doses)	iv	14-28
ACA	Amoxicillin	500-1000 mg tid	po	14-28
	Doxycycline	100 mg bid or 200 mg q24h	po	14-28
	Ceftriaxone	2000 mg q24h	iv	14-28
	Cefotaxime	2000 mg tid	iv	14-28
	Penicillin G	3-4 mu q4h	iv	14-28

EM – erythema migrans, BLC – borrelial lymphocytoma cutis, ACA – atrophic chronic acrodermatitis, bid – twice a day, tid – 3 times a day, po – per os (by mouth), iv – intravenously, q4h – in each 4 h, q24h – in each 24 h