Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Dec 4;8:629. doi: 10.1038/msb.2012.59

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2012, EMBO and Macmillan Publishers Limited

This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.

PMC Copyright notice

Cell surface receptors control Golgi organization. (A) Plot of cis fragmented against cis condensed phenotypic scores for signaling genes. (B) Golgi staining of different compartments in IGF1R and TGFRB1 depletion reveals a typical condensed Golgi phenotype. (C) Golgi staining after cell stimulation with IGF1R ligand IGF1 for 2 h (top) and TGFBR1 ligand TGF-B1 (bottom) or treatment with the IGF1R inhibitor AG1024 for 1 h (middle). Images acquired at × 60 magnification. (D) Quantification for Golgi fragmentation in IGF1 (left) and TGF-B1 stimulation (right) over various time points. Values on graphs indicate the mean±s.e.m. *P<0.05, **P<0.0001 by two-tailed unpaired t-test, relative to untransfected or GFP siRNA-treated cells.