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. 2012 Nov 15;3(11):e426. doi: 10.1038/cddis.2012.168

Table 3. Relative expression of functional gene cluster before and after NOX4 antibody (Ab), ascorbic acid, and ascorbic acid/NOX4 Ab infusion in injured spinal cord tissue.

Description Normal Fold change (P-value)
    ScramRNA/pain NOX4 Ab/pain Ascorbic acid/pain Ascorbic acid/NOX4 Ab/pain
Immunomodulatory factors
 TGFβ1 1.00 0.78 1.88 (P<0.01) 1.03 (NS) 1.38 (P<0.01)
 TGFβ2   0.52 1.45 (P<0.01) 0.73 (NS) 1.08 (P<0.05)
 IL-10   0.46 0.94 (P<0.05) 0.72 (NS) 0.90 (P<0.05)
           
Inflammatory cytokines
 IL-1β 1.00 2.86 1.84 (P<0.05) 2.48 (NS) 1.94 (P<0.05)
           
Redox scavengers
 GPX1 1.00 1.12 1.06 (NS) 1.12 (NS) 1.11 (NS)
 GPX3   0.66 0.92 (P<0.05) 0.94 (P<0.05) 1.04 (P<0.01)
 TXNL1   0.24 1.06 (P<0.05) 0.85 (P<0.05) 1.18 (P<0.05)
 GAPDH   1.03 0.96 (NS) 1.04 (NS) 1.08 (NS)