Table 2. Significance of markers for progression-free survival assessed by univariate and multivariate Cox regression analysis.
| Covariates | Univariate analysis | Multivariate analysis (n=242) |
|---|---|---|
| Del:13 | P=0.03a (n=283) | P=0.546 |
| t4-14 | P=0.05a (n=252) | P=0.515 |
| Del:17p | P=0.08 (n=277) | P=0.457 |
| β2-M >5.5 mg/l | P=0.51 (n=308) | P=0.407 |
| β2-M >3.5 mg/l | P=0.001a (n=308) | P=0.045a |
| Albumin <35 g/l | P=0.153 (n=302) | P=0.828 |
| FLC tertiles | P=0.589 (n=307) | P=0.689 |
| Monoclonal Ig tertilesb | P=0.16 (n=300) | P=0.748 |
| HLC ratios of <200 to >0.01 vs more extreme values | P=0.017a (n=308) | P=0.001a |
Abbreviations: β2-M, β2-microglobulin; FLC, serum free light chain; HLC, immunoglobulin heavy/light chain; Ig, immunoglobulin.
n=number of results available for the analysis.
a
Significant result at P<0.05.
b
Monoclonal immunoglobulins as measured by SPEP densitometry.