Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Minimized, top-ranked GOLD pose of compound 14b in ternary complex with DNA and Top1 (constructed in SYBYL). The ligand is colored in cyan, surrounding structures are colored by element, and hydrogens have been omitted. All distances are measured from heavy-atom to heavy-atom. The same water molecules from Figure 4 are shown as red spheres.
