Skip to main content
. 2013 Jan;94(Pt 1):1–19. doi: 10.1099/vir.0.046508-0

Table 1. List of the published antibodies binding to the gp41 CTT.

na, Not available.

Name of the antibody Targeted region Epitope sequence Epitope characteristics Species/clonality Antibody characteristics References
Chessie 8 KE PDRPEG Conformational Murine IgG Non-neutralizing binds to HIV-infected cells Abacioglu et al. (1994)
SAR1 KE GERDRDR Conformational Murine IgG PAN-neutralizing binds to HIV-infected cells and most virions, no binding to intact NL4.3 virions Reading et al. (2003), Heap et al. (2005), Steckbeck et al. (2010)
EPES (epitope-purified ERDRD specific) KE ERDRD Conformational Murine polyclonal Neutralizing binds to HIV-infected cells and virions Buratti et al. (1998), Cleveland et al. (2000b, 2003)
anti-LLP2 LLP2 na na Rabbit polyclonal IgG na Lu et al. (2008)
1575 KE IEEE Linear immunodominant Murine monoclonal Non-neutralizing binds to HIV-infected cells and virions Buratti et al. (1996, 1997, 1998), Cleveland et al. (2000a), Evans et al. (1989), Heap et al. (2005), Vella et al. (1993)
1577 KE ERDRD Conformational Murine monoclonal IgG Non-neutralizing binding to HIV-infected cells and virions (Dimmock), no binding to intact virions (Steckbeck), epitope binding inhibited by mAb1575 Beaumont et al. (2000), Buratti et al. (1996, 1998), Chomont et al. (2008), Cleveland et al. (2000a, 2003), Evans et al. (1989), Holl et al. (2006), Steckbeck et al. (2010), Vella et al. (1993)
1583 KE ERDRD Conformational Murine monoclonal IgG Non-neutralizing binds to virions Evans et al. (1989), Buratti et al. (1996, 1998), Vella et al. (1993), Cleveland et al. (2003), Heap et al. (2005)