Table 1.
Patients demographics, and their biochemical and histological data at liver biopsy examination (%)
| Characteristics | All patients (n = 246) | HCV patients (n = 195) | HBV patients (n = 41) |
| Sex (men) | 171 (69.5) | 139 (71.3) | 30 (73.2) |
| Age (yr) | 44.7 (11.8)1 | 45.3 (11.5)1 | 41.2 (13.7)1 |
| BMI (kg/m2) | 25.2 (3.9)1 | 25.3 (3.6)1 | 25.2 (5.3)1 |
| AST (IU/L) | 39 (24-78)2 | 40 (26-80)2 | 28 (21-48)2 |
| ALT (IU/L) | 65 (32-116)2 | 70 (35-120)2 | 50 (23-109)2 |
| Platelets count (103/mm3) | 209 (171-262)2 | 212 (176-270)2 | 203 (172-253)2 |
| Fibrosis score (Metavir) | |||
| F0-F1 | 129 (52.3) | 98 (50.3) | 30 (73.2) |
| F2 | 54 (22.0) | 46 (23.6) | 6 (14.6) |
| F3 | 24 (9.8) | 19 (9.7) | 3 (7.3) |
| F4 | 39 (15.9) | 32 (16.4) | 2 (4.9) |
| Steatosis | |||
| S0 (0%) | 157 (63.8) | 126 (64.6) | 26 (63.4) |
| S1 (< 33%) | 56 (22.8) | 44 (22.6) | 10 (24.4) |
| S2 (33%-66%) | 19 (7.7) | 15 (7.7) | 4 (9.8) |
| S3 (> 66%) | 14 (5.7) | 10 (5.1) | 1 (2.4) |
| HAI | |||
| Mild | 109 (44.3) | 80 (41.0) | 28 (68.3) |
| Moderate | 102 (41.5) | 89 (45.7) | 7 (17.1) |
| Severe | 35 (14.2) | 26 (13.3) | 6 (14.6) |
1
mean ± SD
2
Median value and interquartile range (IQR). BMI: Body mass index; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; HAI: Histological activity index; HCV: Hepatitis C virus; HBV: Hepatitis B virus.