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. 2013 Jan 9;33(2):804–813. doi: 10.1523/JNEUROSCI.3729-12.2013

Figure 7.

Figure 7.

PFC output regulates toluene's effect on AMPA/NMDA ratio in mesoaccumbens core DA neurons. A, Microinjection cannula placements in the medial prefrontal cortex. Values are distance from bregma (mm). B, Summary of effects of an intra-mPFC picrotoxin infusion (100 ng) before vapor chamber exposure. **Saline mPFC infusion/5700 PPM toluene group is different from all other groups (p < 0.01 for each comparison, two-way ANOVA, Bonferroni post hoc test). C, Summary of effects of an intra-mPFC muscimol/baclofen infusion (3.5 mg/130 ng) before vapor chamber exposure. *Muscimol/baclofen mPFC infusion/2850 PPM toluene group is different from all other groups (p < 0.05 for each comparison, two-way ANOVA, Bonferroni post hoc test).