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. Author manuscript; available in PMC: 2013 Jan 11.
Published in final edited form as: Adv Pharmacol. 2012;64:27–81. doi: 10.1016/B978-0-12-394816-8.00002-7

FIGURE 1.

FIGURE 1

Chemical structures, lipophilicity (logPoct), Aβ binding affinity (Ki), and brain entry [%Injected Dose Index (%IDI) or (%ID × g body weight)/g brain weight] and brain clearance (2’:30’ ratio) of thioflavin-T, PiB and intervening derivatives. Numbers in parentheses indicate targets for each parameter.