FIGURE 3.

Maintenance of chaperone gene deletion-induced changes in [PIN⁺] variant-dependent phenotypes. Chaperone deletion strains were mated with a wild-type [psi⁻][pin⁻] strain, and the resulting diploids were analyzed for [PSI⁺] induction efficiency, frequency of multiple Rnq1-GFP foci in cells containing foci, and Rnq1p aggregate size. These phenotypes were then categorized as either [PIN⁺]^low/medium or [PIN⁺]^high. Quantifications of [PSI⁺] induction efficiency and frequency of multiple Rnq1-GFP foci in foci-containing cells can be found in supplemental Fig. S2.