FIGURE 6.

Dominance of chaperone gene deletion-induced variants. Diploids were generated by mating chaperone deletion stains with a wild-type [psi⁻] strain carrying the [PIN⁺]^low or [PIN⁺]^medium or [PIN⁺]^high variant. These diploids were analyzed for [PSI⁺] induction efficiency, frequency of multiple Rnq1-GFP foci in foci-containing cells, and Rnq1p aggregate size. These phenotypes were then categorized as either [PIN⁺]^low/medium or [PIN⁺]^high. Quantification of [PSI⁺] induction efficiency and frequency of multiple Rnq1-GFP foci in foci-containing cells can be found in supplemental Fig. S4.