Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Nov 26;288(2):1307–1316. doi: 10.1074/jbc.M112.396317

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 1. — Identification of inhibitory antibodies for rat DPP-IV. A, inhibition of rat DPP-IV by mAbs against rat DPP-IV: inhibition profiles at varying concentrations of a subset of nine good expressers (Ab1–9) from the 13 identified in the alpha screening assay plus two control mAbs (control antibody for irrelevant nonbinding mAb and Ab10 for binding, noninhibitory antibody). B, mAb IC₅₀ values for Ab1, Ab2, and Ab3 toward recombinant rat DPP-IV enzyme: inhibition of DPP-IV-mediated cleavage of GLP-1 by inhibitory antibodies. IC₅₀ was estimated by nonlinear fitting of the percentage of inhibition to mAb concentration.