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. 2012 Nov 29;288(2):928–937. doi: 10.1074/jbc.M112.410241

FIGURE 3.

FIGURE 3.

Genetic interaction between ams2-dKm and histone deacetylases. A, Ams2 shows a genetic interaction with Hst4. Asynchronous wild type (HYY908), ams2-dKm (HYY909), hst4Δ (HYY1032), and hst4Δams2-dKm (HYY1051) cells were spotted with decreasing cell numbers onto rich medium containing 12.5 μg/ml thiabendazole (TBZ) or 12.5 μg/ml trichostatin A (TSA), and incubated at 30 °C for 4 days. B and C, WT (HYY908), ams2-dKm (HYY909), hst4Δ (HYY1032), and hst4Δams2-dKm (HYY1051) cells were incubated in the presence of 50 μg/ml CBZ and “cut” phenotype together with cells with multiple septa were counted at the indicated time points. Error bars, S.E. from three independent experiments.